Frequently Asked Questions: Navexio Diagnostic Navigation Services

  • Navexio can work with cancer patients to assess what diagnostic tests have already been performed, and more importantly what tests have not been performed, and then make recommendations to ensure that all of the appropriate and cutting-edge diagnostics are pursued - specific to your cancer type. Not all tests and technologies are the same, and so Navexio uses its expertise to recommend the most appropriate test(s). This knowledge can provide invaluable guidance towards the most appropriate treatments using precision oncology principles.

  • Navexio will help you identify diagnostic testing that can be pursued using precision oncology principles to ensure every treatment option available for your cancer is being considered. Once test results are received, Navexio will provide recommendations on next steps for your treatment planning to share with your healthcare team.

  • Navexio’s Diagnostic Navigators are focused on optimizing treatment options by ensuring an accurate biomarker signature of the cancer has been attained. This information can provide invaluable and impartial guidance for clients and their medical teams towards the identification of the most appropriate treatments using precision oncology principles.

    • Review of the patient’s medical and molecular / pathology records to assess for gaps in diagnostic work-up, specifically for oncogenomic profiling.

    • Recommend labs/vendors and specific sequencing panels and technologies for appropriate testing for the specific tumour type. (Includes liaising with labs/ vendors on your behalf, if needed).

    • Assess molecular profiling report(s) generated and identify actionable biomarkers (genomic alterations) and their clinical relevance.

    • Provide navigation support and counsel on (follow-up) questions to ask medical team.

    • Navexio offers other services that would not be included in these core services.

  • Navexio wants to help every cancer patient ensure that no stone is left unturned to find the most appropriate cancer treatment. This is fully dependent on a comprehensive cancer diagnostic work-up to discover the root cause of the cancer at the genomic and proteomic levels. A patient’s access to comprehensive diagnostics is dependent on where they live, the testing infrastructure available at their treatment centre, the type and stage of cancer, and/or reimbursement pathways. Precision oncology is a rapidly growing discipline and not all clinicians or patients may be aware of every possible molecular diagnostic test available for their specific cancer type. As a result, most patients do not receive the most current and up-to-date molecular testing available for their cancers, putting them at a disadvantage to the effective management of their cancers.

  • Yes, Navexio can work with you and your oncologist to identify treatments appropriate for you that are approved in your country, treatments that are approved but are prescribed off-label, and/or treatments that are experimental and not yet approved by health authorities. Navexio can also help you navigate the process to access drugs that may only be provided to patients under special access or compassionate programs direct from pharmaceutical companies.

  • Navexio maintains relationships and partnerships with a number of leading diagnostic laboratories globally, including a Canadian distribution partnership with tempus AI. However, this does not mean that Navexio automatically recommends a specific company or test.

    All recommendations are made based on what Navexio believes is in the best interests of the client and their specific cancer. Factors such as cancer type, prior testing, tissue availability, turnaround time, clinical goals, and the strengths of different testing platforms are all considered when determining the most appropriate laboratory and assay.

    Precision oncology is evolving rapidly, and Navexio continuously evaluates new technologies, assays, and laboratories to ensure clients have access to the most appropriate and clinically meaningful testing options available.

  • Navexio consultants are trained biomedical scientists and geneticists with doctorates and post-doctorates that have expertise in molecular oncology, molecular pathology, and molecular diagnostics, along with an intimate understanding of how healthcare systems and pharmaceutical industries operate.

  • Yes, based on your clinical profile and your mobility/ travel flexibility, Navexio can perform a global search and work with you and your healthcare team to find the best clinical trial for you. Clinicians may often only be familiar with trials within their institution or city, but Navexio will work with you to identify which trials you may be eligible for and can provide you with ongoing monitoring for new trials. Given that trial navigation often needs to be done with urgency, Navexio can also help you explore strategies that will make the selection process and eligibility matching more efficient.

Find other FAQs for Navexio’s Services here.

If you have other diagnostic navigation or cancer support questions for Navexio that are not answered above or require additional information, please reach-out here.